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What is Stevens Johnson Syndrome?

Stevens Johnson Syndrome (SJS) was first identified in 1922 by A.M. Stevens and S.C. Johnson. SJS is an immune complex mediated hypersensitivity disorder that may be caused by many drugs, viral infections and malignancies. Patients who develop SJS often develop large blisters in the mouth, throat, on the skin, around the anus or genitals, and even on the eyes. The blisters rupture, leaving the skin and nerve endings exposed causing severe pain. Although the severity and nature of the symptoms may vary, as many as 10% of patients develop blindness and as many as 15% of patients die from SJS.

Causes of  Steven Johnson Syndrome

At Nadrich & Cohen, LLP our attorneys have experience successfully representing seriously injured clients against large pharmaceutical corporations. If you or a loved one are suffering from Stevens-Johnson Syndrome as the result of a prescription or over-the-counter medication, you should hire aggressive legal representation immediately. Our personal injury attorneys have recovered more than $75,000,000 for our clients nationwide. Please contact Nadrich & Cohen, LLP today to discuss your dangerous drug case with one of our pharmaceutical litigation attorneys. Unfortunately, the cause for about half of all cases of Stevens-Johnson Syndrome cannot be determined by medical professionals. However, when a cause can be determined, bacterial infections and allergic reactions associated with use of certain medicines are found to be causes.

Approximately one hundred different drugs have been associated with Stevens-Johnson Syndrome. Listed below are a few of the drugs and drug types that have been linked to SJS and TEN:

  • Allopurinol (enzyme blocker used to treat gout and kidney stones)
  • Amoxicillin (antibiotic medicine)
  • Ampicillin (antibiotic medicine)
  • Arava (drug used to treat rheumatoid arthritis)
  • Carbamazepine (drug used to treat epilepsy and mania)
  • Children’s Motrin (over-the-counter drug used to treat cold, flu, fever, pain in children)
  • Anticonvulsant/Antiepileptic (drugs used to prevent seizures and tremors, such as Phenobarbital, Phenytoin, and Tegretol)
  • Barbituates (drugs that lessen brain activity in an effort to help people relax)
  • COX-2 inhibitors (anti-inflammatory drugs)
  • Nonsteroidal anti-inflammatory drugs (NSAIDS) (anti inflammatory drugs which block COX-2 enzymes, such as Valdecoxib)
  • Sulfa drugs (group of antibiotics used to treat fungal and bacterial infections)
  • Tetracyclines (antibacterial drugs)

Recent cases of Stevens-Johnson Syndrome affecting children have been linked to the use of Children’s Motrin, a commonly used and widely available over-the-counter medication. In fact, Sabrina Brierton Johnson, a 7 year old girl from California, has filed a lawsuit against McNeil Consumer & Specialty Pharmaceuticals, makers of Children’s Motrin, claiming that her use of the drug made her blind. A variety of other defendants have been named in this case, including Johnson & Johnson for not including a Stevens-Johnson Syndrome warning on the packaging label.

Treatment for SJS 

The experienced and aggressive nationwide dangerous drug attorneys at Nadrich & Cohen, LLP aggressively handle all Stevens-Johnson Syndrome and Children’s Motrin side effects cases nationwide. Our pharmaceutical litigation lawyers are prepared to represent seriously injured clients against even the biggest pharmaceutical manufacturers. The personal injury lawyers at Nadrich & Cohen, LLP have recovered in excess of $250,000,000 for our injured clients throughout the country. If your loved one has suffered the serious symptoms of Stevens-Johnson Syndrome, please contact a drug litigation lawyer at Nadrich & Cohen, LLP today to discuss your case.

Modes of treatment to heal Stevens-Johnson Syndrome vary depending upon the severity of the disorder and the symptoms of each individual patient. Many patients with SJS or Toxic Epidermal Necrolysis typically require hospitalization to ensure that they receive proper treatment and care.

A patient who has a skin infection or lesions may be advised to enter a burn care facility and take antibiotics and other medications or ointments to alleviate pain and heal the skin. In certain situations, patients are treated with high doses of corticosteroids to reduce skin inflammation, although some people may have a negative reaction and get an infection. In severe cases, patients with SJS or TEN related skin conditions and rashes may have to live with permanent scarring on affected areas.

Vision problems are typically secondary conditions associated with SJS, and treatments are available. It has been estimated that 25% of people who have Stevens-Johnson Syndrome may experience long term vision damage or vision loss. Some patients who experience eye and vision problems within the first two weeks of developing Stevens-Johnson Syndrome undergo amniotic membrane transplants.

Treatments that are essential to the management of Stevens-Johnson Syndrome can be very expensive. By hiring an aggressive law team to represent your rights as a victim of Stevens-Johnson Syndrome, you may be able to recover monetary compensation for your injuries and injury related expenses, such as reimbursement for medical bills, hospital visits, and surgeries.

Nationwide SJS Lawyers

Resource Information For Stevens Johnson Syndrome

Intravenous ulinastatin therapy for Stevens-Johnson syndrome and toxic epidermal necrolysis in pediatric patients. Three case reports.

PubMed, National Library of Medicine, Int Arch Allergy Immunol 2002 Jan;127(1):89-94, Inamo Y, Okubo T, Wada M, Fuchigami S, Hashimoto K, Fuchigami T, Takahashi S, Sawada S, Harada K, Department of General Pediatrics, Nihon University Nerima-Hikarigaoka Hospital, Nihon University School of Medicine, Tokyo, Japan. [email protected]


Stevens-Johnson Syndrome and Cholestatic Hepatitis.

PubMed, National Library of Medicine, Digestive Diseases and Sciences, Vol. 46, No. 11 (November 2001):2385-8, Michael S. Morelli, MD and Francis X. O’Brien, MD. Department of Internal Medicine, Section of General Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.


Drug-associated acute-onset vanishing bile duct and Stevens-Johnson syndromes in a child.

PubMed, Srivastava M, Perez-Atayde A, Jonas MM. Combined Program in Gastroenterology, Department of Medicine, Children’s Hospital, Boston, Massachusetts, USA., Gastroenterology. 1998 Sep;115(3):743-6.PMID: 9721172.


Acute and Chronic Respiratory Complications of Toxic Epidermal Necrolysis.

PubMed, National Library of Medicine, J Burn Care Rehabilitation 1996 May-Jun;17(3):237-40, R.A. McIvor, MD; J. Zaidi, MD; W. J. Peters, MD; R.H.Hyland, MD. Division of Respirology, University of Toronto, and the Ross Tilley Burn Centre, Wellesley Hospital, Toronto, Ontario, Canada.


Bronchiolitis obliterans in children with Stevens-Johnson syndrome: follow-up with high resolution CT.

PubMed, National Library of Medicine, Pediatrics Radiology 1996;26(1):22-5, M.J. Kim and K.Y. Lee. Department of Diagnostic Radiology, Severance Hospital, 134 Seodaemoon-gu, Shinchon-dong, Seoul 120-752, Korea.


Stevens-Johnson syndrome plus toxic hepatitis due to ibuprofen.

PubMed, National Library of Medicine, New York State Journal of Medicine July;78(8):1239-43, Sternlieb P, Robinson RM. Nassau Hospital, Mineola, New York


Esophageal Involvement in Stevens-Johnson Syndrome.

PubMed, National Library of Medicine, Endoscopy 2001 Jun;33(6):550-3, Lamireau T, Leaute-Labreze C, Le Bail B, Taieb A., Division of Pediatric Gastroenterology, Children ‘s Hospital, Bordeaux, France. [email protected] Division of Pediatric Dermatology, Children’s Hospital, Bordeaux, France, Laboratory of Pathology, Pellegrin’s Hospital, Bordeaux, France.

If you or your child has suffered Stevens Johnson Syndrome or Toxic Epidermal Necrolysis from taking Children’s Motrin, Dilantin or Lamictal or other medications, please contact an SJS lawyer at Nadrich & Cohen, LLP immediately. We are representing Stevens Johnson Syndrome victims nationwide.

Call us at 1-800-722-0765 for immediate assistance or click here to submit your potential case.

We are available 7 days a week and will respond to your inquiry within 24 hours.

 

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